Table 5.

Adjusted incidence rate ratio for all-cause mortality per 10-ml/min per 1.73 m2 lower eGFR: NHANES III

ParameterOverallFemaleMaleP (Interaction)
eGFR <60 ml/min per 1.73 m2, based on:
    creatinine, age, race, and gender1.25 (1.31 to 1.37)1.36 (1.19 to 1.56)1.14 (0.99 to 1.32)0.05
    cystatin C1.32 (1.23 to 1.42)1.31 (1.18 to 1.45)1.32 (1.19 to 1.46)0.77
    cystatin C, age, race, and gender1.35 (1.27 to 1.44)1.41 (1.29 to 1.54)1.29 (1.17 to 1.42)0.13
    creatinine, cystatin C, age, race, and gender1.31 (1.21 to 1.42)1.37 (1.23 to 1.52)1.23 (1.10 to 1.39)0.13
eGFR 60 to 90 ml/min per 1.73 m2, based on:
    creatinine, age, race, and gender1.00 (0.91 to 1.09)0.98 (0.86 to 1.11)1.01 (0.89 to 1.14)0.54
    cystatin C1.23 (1.11 to 1.35)1.25 (1.08 to 1.45)1.22 (1.07 to 1.40)0.78
    cystatin C, age, race, and gender1.29 (1.16 to 1.44)1.24 (1.04 to 1.49)1.35 (1.18 to 1.56)0.80
    creatinine, cystatin C, age, race, and gender1.12 (1.02 to 1.23)1.13 (0.98 to 1.30)1.13 (0.99 to 1.28)0.99
ParameterBlackNonblackP (Interaction)Age <65Age ≥65P (Interaction)
eGFR <60 ml/min per 1.73 m2, based on:
    creatinine, age, race, and gender1.24 (1.00 to 1.53)1.24 (1.11 to 1.38)0.831.26 (0.88 to 1.81)1.25 (1.12 to 1.38)0.41
    cystatin C1.22 (1.02 to 1.46)1.32 (1.22 to 1.44)0.621.30 (0.98 to 1.71)1.32 (1.22 to 1.43)0.92
    cystatin C, age, race, and gender1.31 (1.10 to 1.56)1.34 (1.25 to 1.44)0.911.47 (1.12 to 1.93)1.34 (1.25 to 1.43)0.08
    creatinine, cystatin C, age, race, and gender1.28 (1.07 to 1.53)1.30 (1.19 to 1.42)0.621.43 (1.04 to 1.97)1.30 (1.20 to 1.41)0.22
eGFR 60 to 90 ml/min per 1.73 m2, based on:
    creatinine, age, race, and gender1.01 (0.79 to 1.28)0.99 (0.90 to 1.09)0.610.97 (0.76 to 1.25)1.00 (0.91 to 1.10)0.63
    cystatin C1.29 (1.04 to 1.60)1.22 (1.09 to 1.36)0.911.01 (0.80 to 1.29)1.27 (1.14 to 1.42)0.04
    cystatin C, age, race, and gender1.48 (1.19 to 1.84)1.23 (1.09 to 1.40)0.781.30 (1.04 to 1.64)1.29 (1.13 to 1.46)0.36
    creatinine, cystatin C, age, race, and gender1.11 (0.88 to 1.40)1.13 (1.01 to 1.25)0.311.21 (0.94 to 1.56)1.11 (1.00 to 1.23)0.80