Table 1.

Morphometric analyses and renal function tests: BM infusion

ParameterKO + WT BMKO + KO BMStatistical Significance
Urine albumin-creatinine ratio
    20 wk36.6 ± 12.044.0 ± 3.2No
    21 wk28.8 ± 4.584.0 ± 23.3a
    22 wk44.2 ± 9.599.6 ± 8.1a
    23 wk54.2 ± 11.294.3 ± 22.9P = 0.2
Morphometric analyses (%)
    normal glomeruli22.3 ± 0.46.5 ± 0.9P = 0.07
    global glomerular sclerosis70.9 ± 3.480.0 ± 2.7a
    tubular atrophy44.4 ± 3.682.1 ± 1.6b
    relative interstitial volume30.3 ± 2.556.4 ± 2.8b