Table 2.

Morphometric analyses and renal function tests: Blood transfusion

ParameterMorphometric Analyses (%)Renal Function Tests
Normal GlomeruliTubular AtrophyRelative Interstitial VolumeSerum BUN (mg/dl)Urine Albumin-Creatinine Ratio
Early transfusion
    WT99.6 ± 0.40.1 ± 0.16.6 ± 0.322.5 ± 6.50.5 ± 0.1
    KO at 12.5 wk75.8 ± 4.522.6 ± 6.416.1 ± 2.051.0 ± 15.112.2 ± 3.7
    KO + 8 wk transfusion97.7 ± 1.25.4 ± 3.09.0 ± 2.429.9 ± 2.92.5 ± 0.9
Statistical significanceaaaaa
Late transfusion
    WT98.9 ± 0.30.1 ± 0.16.9 ± 0.633.5 ± 2.91.5 ± 0.8
    KO22.4 ± 4.177.3 ± 5.233.4 ± 3.2316 ± 19.925.8 ± 3.9
    KO + 23 wk KO transfusion20.3 ± 6.892.6 ± 1.731.8 ± 4.7363 ± 3.922.6 ± 2.7
    KO + 23 wk WT transfusion36.3 ± 8.719.2 ± 3.916.9 ± 5.18203 ± 60.217.3 ± 3.8
Statistical significanceaaaaNo