Table 4.

Morphometric analyses and renal function tests: mESC studies

ParameterWTKOKO + mESCsStatistical Significance
Urine albumin-creatinine ratio
    12 wk0.5 ± 0.0812.2 ± 3.72.2 ± 0.2a
    21 wk1.5 ± 0.825.8 ± 3.97.4 ± 2.1a
BUN49.2 ± 3.6316.7 ± 19.9112.7 ± 1.2a
Morphometric analyses (%)
    normal glomeruli98.9 ± 0.322.4 ± 4.144.7 ± 19.9a
    tubular atrophy0.1 ± 0.177.3 ± 5.223.0 ± 4.0a
    relative interstitial volume6.9 ± 0.633.4 ± 3.223.9 ± 3.6a