Table 1.

Baseline characteristics of the 1038 cohort patientsa

CharacteristicValue
Age (yr; mean ± SD)59 ± 15
Men (%)69
Black (%)6
Renal disease (% biopsy-proven)a
    vascular nephropathy34 (10)
    glomerulonephritis19 (55)
    diabetic kidney disease13 (10)
    tubulointerstitial nephritis11 (20)
    polycystic kidney disease5 (0)
    undetermined17 (5)
BMI (%; kg/m2)
    <2543
    25 to 3037
    ≥3020
Diabetes (%)26
BP ≥130/80 mmHg (%)65
Any antihypertensive treatment (%)92
ACEi or ARB treatment (%)77
Albuminemia (g/L; mean ± SD)39.5 ± 5.1
Proteinuria (%; g/g creatinine)
    <0.553
    0.5 to 1.015
    ≥1.032
mGFR (ml/min per 1.73 m2; mean ± SD)37 ± 17
eGFRcl (ml/min per 1.73 m2; mean ± SD)38 ± 17
eGFRms (ml/min per 1.73 m2; mean ± SD)36 ± 16
CKD stages based on mGFR/eGFRcl/eGFRms (%)
    2 (60 to 89 ml/min per 1.73 m2)12/10/7
    3 (30 to 59 ml/min per 1.73 m2)48/55/53
    4 (15 to 29 ml/min per 1.73 m2)31/28/31
    5 (<15 ml/min per 1.73 m2, not on dialysis)9/7/9
  • a Percentages in parentheses are those of biopsy-proven diagnoses among patients with each type of renal disease. mGFR, measured glomerular filtration rate; eGFRcl, estimated glomerular filtration rate, using the MDRD Study equation with serum creatinine values calibrated by the Cleveland Clinic Laboratory; eGFRms, eGFR using the MDRD equation with serum creatinine values standardized to mass spectrometry.