Table 3.

Adjusted HR (95% CIs) of CHD and all-cause mortality by quartiles of % annual change in eGFR from visit 1 to visit 4

OutcomesQuartiles of % Annual Change in eGFR
Q1 (−25.53 to −2.46)Q2 (−2.46 to −0.74)Q3 (−0.74 to −0.56)Q4 (−0.56 to 13.54)
Adjustment for covariates at visit 1
    na2326231623392335
    CHD1.32 (1.08 to 1.63)1.06 (0.86 to 1.30)Reference1.18 (0.97 to 1.45)
    all-cause mortality1.41 (1.16 to 1.72)1.11 (0.90 to 1.36)Reference1.11 (0.90 to 1.36)
Adjustment for covariates at visit 4
    na1190113011311048
    CHD1.17 (0.87 to 1.58)1.11 (0.84 to 1.48)Reference1.32 (0.99 to 1.74)
    all-cause mortality1.27 (0.97 to 1.67)0.98 (0.74 to 1.30)Reference1.05 (0.80 to 1.39)
  • Adjusted for following covariates at either visit: Age, race, gender, level of education, carotid atherosclerosis, SBP, antihypertensive medication, diabetes, smoking, alcohol intake, BMI, LDL cholesterol, HDL cholesterol, left ventricular hypertrophy, and eGFR.

  • aParticipants included in the fully adjusted analysis.