Table 1.

Characteristics at baseline of participants with and without subsequent rapid decline in kidney function based on cystatin C

Characteristic(−) Rapid Decline by eGFRcys(n = 3295)(+) Rapid Decline by eGFRcys(n = 1083)P
Age at baseline (yr; mean ± SD)72 ± 573 ± 5<0.001
Age at final cystatin C measurement (yr; mean ± SD)78 ± 578 ± 50.69
Female gender (n [%])1965 (60)644 (60)0.92
Black race (n [%])398 (12)186 (17)<0.001
Body mass index (kg/m2; mean ± SD)27 ± 527 ± 50.84
Tobacco use, current or former (n [%])1746 (53)591 (55)0.36
Diabetes (n [%])412 (13)204 (19)<0.001
Hypertension (n [%])1330 (40)517 (48)<0.001
SBP (mmHg; mean ± SD)134 ± 20141 ± 22<0.001
DBP (mmHg; mean ± SD)71 ± 1172 ± 110.01
LDL cholesterol (mg/dl; mean ± SD)130 ± 35130 ± 360.66
HDL cholesterol (mg/dl; mean ± SD)54 ± 1655 ± 160.13
Triglycerides (mg/dl; median [interquartile range])122 (92, 166)118 (90, 163)0.96
C-reactive protein (mg/L; median [interquartile range])2.41 (1.23, 4.27)2.32 (1.18, 4.46)0.12
Self-reported health fair/poor (n [%])562 (18)232 (24)<0.001
Baseline eGFRcys (ml/min per 1.73 m2; mean ± SD)77 ± 1885 ± 21<0.001
Final measure of eGFRcys (ml/min per 1.73 m2; mean ± SD)72 ± 1861 ± 19<0.001
Baseline eGFRcreat (ml/min per 1.73 m2; mean ± SD)79 ± 2282 ± 24<0.001
Final measure of eGFRcreat (ml/min per 1.73 m2; mean ± SD)81 ± 2270 ± 24<0.001
  • DBP, diastolic BP; SBP, systolic BP.