Table 3.

Proteins of the ESCRT complex found in human urinary exosomesa

GeneProtein NamePepIDRef SeqESCRT Complex
HGSHepatocyte growth factor–regulated tyrosine kinase substrate11NP_004703ESCRT-0
TSG101Tumor susceptibility gene 1011547NP_006283ESCRT-I
VPS28Vacuolar protein sorting 28 isoform 158NP_057292ESCRT-I
VPS28Vacuolar protein sorting 28 isoform 228NP_898880ESCRT-I
VPS37BVacuolar protein sorting 37B410NP_078943ESCRT-I
VPS37CVacuolar protein sorting 37C11NP_060436ESCRT-I
VPS25EAP25415NP_115729ESCRT-II
VPS36EAP4523NP_057159ESCRT-II
SNF8EAP3011NP_009172ESCRT-II
CHMP2ACHMP2A640NP_055268ESCRT-III
CHMP2BCHMP2B311NP_054762ESCRT-III
VPS24CHMP313NP_057163ESCRT-III
VPS24CHMP314NP_001005753ESCRT-III
CHMP4BCHMP4B26NP_789782ESCRT-III
CHMP5CHMP527NP_057494ESCRT-III
CHMP1ACHMP1A13NP_002759ESCRT-III
CHMP1BCHMP1B12NP_065145ESCRT-III
CHMP6CHMP623NP_078867ESCRT-III
VPS4AVacuolar protein sorting factor 4A1125NP_037377ATPase complex
VPS4BVacuolar protein sorting factor 4B1132NP_004860ATPase complex
PDCD6IPALIX27104NP_037506Accessory
C1orf58Hypothetical protein LOC1483621134NP_653296Accessory
  • ↵a Table contains all of the proteins that are members of the ESCRT Complex (ESCRT-0, ESCRT-I, ESCRT-II, ESCRT-III, ATPase complex and accessory).