Table 3.

Time (hours) to reach within 0.1 mg/dl of predicted steady-state SCr concentration after a given reduction in CrCla

ParameterReduction in CrCl
75%50%25%
No CKD1023410
Stage 2 CKD1595921
Stage 3 CKD22313962
  • a Results were obtained using a two-compartment model of creatinine kinetics.