Table 5.

Application of published and CKiD prediction equations to testing data set of 168 children of the CKiD study at first follow-up visit with iGFR 40.47 ± 16.10 ml/min per 1.73 m2

ModelData SourceeGFRaBiasb95% LOAcCorrelation% of eGFR within 30% of iGFR% of eGFR within 10% of iGFR
Scr-based formulas
    Counahan et al.2Original40.32 ± 17.01−0.15−18.5, 18.20.847132
CKiDd38.73 ± 16.34−1.75−19.7, 16.20.847326
    Leger et al.35Original54.37 ± 25.3913.90−17.7, 45.50.794513
CKiD38.95 ± 18.06−1.52−23.3, 20.20.797129
Cystatin C–based formulas
    Filler et al.36Original42.46 ± 18.001.99−20.6, 24.60.786526
CKiD38.18 ± 11.21−2.30−22.5, 17.90.777237
    Grubb et al.27Original35.45 ± 22.47−5.02−33.0, 22.90.784314
CKiD38.28 ± 11.34−2.19−22.6, 18.20.767233
Scr and cystatin C–based formulas
    Bouvet et al.20Original51.50 ± 18.7011.03−11.1, 33.10.804815
CKiD38.31 ± 13.26−2.17−18.1, 13.80.868038
    Zappitelli et al.21Original34.86 ± 15.65−5.61−22.3, 11.10.866532
CKiD38.27 ± 13.43−2.20−17.8, 13.40.878238
    CKiD equation IIIeCKiD38.25 ± 13.57−2.23−17.1, 12.70.888341
  • a eGFR, ml/min per 1.73 m2. LOA, limits of agreement.

  • b Bias = average of 168 (eGFR − iGFR) values, in ml/min per 1.73 m2.

  • c 95% LOA = bias ± 1.96 × SD of (eGFR − iGFR).

  • d Updated Schwartz from Table 3.

  • e Equation III from Table 3: 39.1[ht/Scr]0.516[1.8/CysC]0.294[30/BUN]0.169[1.099male][ht/1.4]0.188.