Table 1.

Patient characteristics at enrollment

CharacteristicAll Patients(n = 647)High-Flux(n = 318)Low-Flux(n = 329)
Age (yr; mean ± SD)59.8 ± 13.659.4 ± 14.560.2 ± 12.7
Male gender (n [%])415 (64.1)200 (62.9)215 (65.3)
Diabetes (n [%])157 (24.2)83 (26.1)74 (22.5)
Cardiovascular diseases (n [%])174 (26.9)81 (25.5)93 (28.3)
Charlson comorbidity index (mean ± SD)a4.6 ± 2.14.5 ± 2.24.6 ± 2.0
Time on dialysis (d; mean ± SD)30 ± 1831 ± 1829 ± 19
Body mass index (kg/m2; mean ± SD)25.3 ± 4.325.2 ± 4.325.3 ± 4.3
Urine volume >100 ml/24 h (n [%])465 (71.9)222 (69.8)243 (73.9)
Vascular access (n [%])
    fistula518 (80.1)246 (77.3)272 (82.7)
    graft30 (4.6)13 (4.1)17 (5.2)
    catheter99 (15.3)59 (18.6)40 (12.2)
spKt/V (mean ± SD)b1.36 ± 0.301.36 ± 0.301.35 ± 0.30
Serum albumin (g/dl; mean ± SD)b3.8 ± 0.53.9 ± 0.53.8 ± 0.5
  • a Charlson comorbidity index was calculated excluding diabetes.

  • b Month 0.