Table 3.

Adjusted risks of end-stage kidney disease, macrovascular events, cardiovascular death, and all-cause death by baseline albuminuria levela

End PointNormoalbuminuria (n = 7877)Micro- or Macroalbuminuria (n = 3263)HR (95% CI)
End-stage kidney diseaseb19 (0.2%)27 (0.8%)1.99 (1.08 to 3.70)
Macrovascular eventsc585 (7.4%)415 (12.7%)1.61 (1.42 to 1.84)
Cardiovascular death239 (3.0%)229 (7.0%)2.07 (1.72 to 2.50)
All-cause death496 (6.3%)383 (11.7%)1.70 (1.48 to 1.96)
  • a Adjusted for age, gender, HbA1c, SBP, DBP, LDL cholesterol, HDL cholesterol, triglycerides, BMI, eGFR, current smoking, and current alcohol use.

  • b Defined as requirement of renal replacement therapy or renal death.

  • c Composite of nonfatal myocardial infarction, nonfatal stroke, or cardiovascular death.