Table 1.

Relationship between renal function at the time of biopsy or functional deterioration and histologic lesions

Histologic LesionsaSpearman Correlation Coefficient
Function at the Time of BiopsybFunctional Change from Baseline to Biopsyb
g0.010−0.130
cg0.0950.088
i−0.080−0.171*
ci−0.189*0.093
t0.029−0.251**
ct−0.162*0.055
v0.149−0.082
cv0.0470.158
ah0.0840.241**
mm−0.0060.058
ptc0.049−0.190*
ptcml−0.1590.162
  • a g-score, glomerulitis; cg-score, glomerulopathy; i-score, inflammation; ci-score, interstitial fibrosis; t-score, tubulitis; ct-score, tubular atrophy; v-score, intimal arteritis, cv-score, vascular fibrous intimal thickening; ah-score, arteriolar hyaline thickening; mm-score, mesangial matrix increase; ptc-score, peritubular capillaritis; ptcml, peritubular basement membrane multilayering.

  • b delta GFR = eGFR at biopsy − eGFR at baseline; thus negative delta GFR values indicate loss of function.

  • * P < 0.05;

  • ** P < 0.001.