Table 1.

Characteristics of participants in the HUNT 2 study at baseline (1995 through 1997) by future progression or no progression to ESRDa

CharacteristicAll (n = 65,589)No Progression to ESRD (n = 65,465)Progression to ESRD (n = 124)P
Age (yr; mean [SD]; n = 65,589)50.1 (17.3)50.1 (17.3)70.8 (13.4)<0.001
Male gender (%; n = 65,589)46.846.862.9<0.001
Low education (%; n = 61,369)b70.770.686.5<0.001
Depression (%; n = 58,423)c10.610.626.5<0.001
Current smoking (%; n = 64,395)28.028.017.60.012
Low physical activity (%; n = 57,881)d20.120.142.7<0.001
Diabetes (%; n = 64,693)3.33.318.2<0.001
CVD (%; n = 64,624)e7.97.925.8<0.001
BMI (kg/m2; mean [SD]; n = 64,306)26.4 (4.1)26.4 (4.1)28.0 (5.0)<0.001
Waist circumference (cm; mean [SD]; n = 64,022)86.5 (11.8)86.5 (11.8)94.1 (13.6)<0.001
Systolic BP (mmHg; mean [SD]; n = 64,708)137.9 (21.8)137.9 (21.8)160.6 (24.9)<0.001
Diastolic BP (mmHg; mean [SD]; n = 64,708)80.3 (12.3)80.3 (12.2)87.3 (15.8)<0.001
Antihypertensive medication (%; n = 64,649)11.111.046.7<0.001
Cholesterol (mg/dl; mean [SD]; n = 65,158)228.2 (48.9)228.2 (50.3)252.4 (58.0)<0.001
HDL cholesterol (mg/dl; mean [SD]; n = 65,155)53.2 (15.1)54.1 (15.5)46.4 (15.4)<0.001
Triglycerides (mg/dl; median [range]; n = 65,158)131 (12–696)131 (12–696)187 (35–363)<0.001
Glucose (mg/dl; median [range]; n = 65,158)f93 (41–558)94 (41–558)102 (61–348)<0.001
Creatinine (mg/dl; mean [SD]; n = 65,158)1.0 (0.2)1.0 (0.2)1.7 (0.6)<0.001
eGFR (ml/min per 1.73 m2; mean [SD]; n = 65,158)94.2 (21.5)94.3 (21.5)49.8 (23.5)<0.001
ACR (mg/g; median [range]; n = 9703)7 (0.4–2437)7 (0.4–1558)136 (94.4–2437)<0.001
  • a The “no progression” and “progression” groups are compared using χ2 test or two-samplet test. BMI, body mass index; CVD, cardiovascular disease.

  • b Fewer than 12 yr in school.

  • c Eight points or more on the depression part of the Hospital Anxiety and Depression Score.

  • d Less than 1 h of light activity per week in participants’ leisure time.

  • e Self-reported history of myocardial infarction, angina pectoris, or stroke.

  • f Measured at random.