Table 2.

Clinical characteristics at presentation

CharacteristicValue
Peripheral edema (n [%])23 (62.2)
24-h urine protein (g/d; mean [range])5.70 (0.36 to 17.00)
    Proteinuria <1 g/24 h (n [%])1/35 (2.9)
    Proteinuria 1–3g/24 h (n [%])10/35 (28.6)
    Proteinuria >3g/24 h (n [%])24/35 (68.6)
Full nephrotic syndrome (n [%])17/35 (48.6)
Serum albumin (g/dl; mean [range])3.1 (1.1 to 4.9)
Hematuria (n [%])27/35 (77.1)
Serum creatinine at biopsy (mg/dl; mean [range])2.77 (0.70 to 17.00)
    Renal insufficiency at presentation (n [%])25 (67.6)
Evidence of dysproteinemia (n [%])a11/37 (29.7)
    Serum paraprotein only4
    Serum and urine paraprotein7
    Multiple myeloma1
    AL-amyloid1
Low C3 (n [%])3 (8.1)
Low C4 (n [%])3 (8.1)
Low C3 and C4 (n [%])4 (10.8)
Positive serum cryoglobulin (n [%])b0 (0.0)
Positive hepatitis C antibody (n [%])1/30 (3.3)
Positive rheumatoid factor (n [%])1/18 (5.5)
  • aIn one patient, M-spike was not detected until 3 yr after presentation.

  • bPerformed repeatedly.