Table 1.

Baseline characteristics among ARIC participants stratified by any occurrence of AKI hospitalizationa

CharacteristicsTotal Cohort
No AKI HospitalizationAKI Hospitalization
n10844356
Percent96.8%3.2%
Age (mean)62.864.7
Female (%)56.048.3
Race (% black)21.734.6
Diabetes (%)16.039.9
Hypertension (%)46.770.4
Obese (%)34.648.7
Current smoking (%)14.718.2
Baseline ACEI/ARB (%)12.127.5
Prior cardiovascular event (%)8.124.7
Prior AKI event (%)b0.20.6
MDRD GFR (median)81.072.2
CKD-EPI GFR (median)86.475.4
Stage 3 to 4 CKD by MDRD (%)7.627.5
Stage 3 to 4 CKD by CKD-EPI (%)5.925.0
UACR (mean)23.2207.1
Microalbuminuria (%)6.216.9
Macroalbuminuria (%)1.313.2
Mean follow-up, years8.17.0
Number of admissions, mean1.36.0
Deaths (%)9.352.8
  • aAll P values <0.001 with the exception of % female (P = 0.004), % current smoking (P = 0.1), % prior known AKI event (P = 0.1).

  • bPrior AKI event defined as an AKI hospitalization since enrollment in the ARIC study but before study visit 4.