Table 1.

Comparison of baseline patient characteristics

CharacteristiceGFR <60(n = 524)eGFR ≥60(n = 966)P
Age<0.001
    >65 yr (%)73.344.4
    mean (range)69 (38 to 89)64 (31 to 85)
Female gender (%)37.627.1<0.001
Black race (%)1.53.80.01
Qualifying (presenting) ischemic event (%)
    stroke (not TIA)41.238.80.37
    hemispheric (not retinal)72.171.30.74
History of (%)
    TIA or stroke within past 6 moa54.855.70.73
    hypertension73.754.3<0.001
    diabetes22.521.00.50
    MI24.018.00.006
    CHF3.82.00.03
    arrhythmia4.25.30.36
    hyperlipidemia35.734.50.64
    intermittent claudication17.013.80.10
Smoking within past 12 mo (%)34.550.2<0.001
Systolic BP >160 mmHg (%)23.516.70.001
Diastolic BP >90 mmHg (%)13.012.00.59
Glucose >7 mmol/L (>126 mg/dl) (%)20.021.20.59
Degree of ICA stenosis 70 to 99% (%)41.444.50.25
eGFR (ml/min per 1.73 m2; mean [range])49 (19 to 60)79 (60 to 153)
Serum creatinine (μmol/L; mean [range])127 (86 to 292)87 (39 to 133)
Serum creatinine (mg/dl; mean [range])1.5 (0.9 to 3.3)1.0 (0.4 to 1.5)
  • Characteristics were compared using a χ2 test. TIA, transient ischemic attack; ICA, internal carotid artery stenosis; MI, myocardial infarction.

  • aIn addition to the qualifying (presenting) event.