Table 4.

30-Day perioperative risks of outcomes by CKD status (eGFR, ml/min per 1.73 m2) for patients assigned to carotid endarterectomy (n = 744)

ParametereGFR <60 (%; n = 245)eGFR ≥60 (%; n = 499)Risk Difference (%; 95% CI)P
Any stroke or death6.96.40.5 (−3.3 to 4.4)0.79
Any nonfatal stroke4.95.6−0.7 (−4.1 to 2.7)0.68
Death (any cause)2.00.81.2 (−0.7 to 3.2)0.15
MI, CHF, or arrhythmia6.51.25.3 (2.1 to 8.6)<0.001
MI2.00.61.4 (−0.5 to 3.3)0.07
CHF1.60.21.4 (−0.2 to 3.1)0.025
Arrhythmia3.60.63.0 (0.6 to 5.5)0.002
  • Includes patients who had moderate and severe stenoses at time of randomization and actually had surgery. Patients with and without CKD were compared using a χ2 test.