Table 1.

Urinary and blood parameters from mice kept on a standard-salt diet

ParameterKOControl
Body weight (g)
    females21.30 ± 0.66 (n = 13)22.10 ± 0.65 (n = 24)
    males27.70 ± 0.89 (n = 13)28.20 ± 1.08 (n = 15)
Food intake (g/g body wt per 24 h)0.13 ± 0.01 (n = 8)0.12 ± 0.01 (n = 10)
Na+ intake (mmol/24 h)0.27 ± 0.03 (n = 8)0.26 ± 0.03 (n = 10)
Urinary Na+ (mmol/24 h)0.23 ± 0.01 (n = 31)a0.19 ± 0.01 (n = 46)
Urinary Na+ (mM)136 ± 11 (n = 31)155 ± 7 (n = 46)
Urinary K+ (mmol/24 h)0.33 ± 0.04 (n = 31)0.28 ± 0.03 (n = 46)
Urinary K+ (mM)213 ± 38 (n = 31)242 ± 23 (n = 46)
Urinary osm (mosm/kgH2O)1809 ± 119 (n = 26)b2442 ± 133 (n = 39)
Urine output (ml/g body wt per 24 h)0.085 ± 0.008 (n = 31)b0.055 ± 0.004 (n = 46)
Water intake (ml/g body wt per 24 h)0.25 ± 0.03 (n = 31)a0.16 ± 0.01 (n = 46)
Serum osm (mosm/kgH2O)309 ± 4 (n = 5)313 ± 34 (n = 6)
Serum Na+ (mM)145.8 ± 1.0 (n = 5)a149.8 ± 1.1 (n = 6)
Plasma/serum K+ (mM)6.3 ± 0.2 (n = 10)a5.6 ± 0.1 (n = 16)
Mean BP (mmHg)127 ± 2 (n = 13)135 ± 3 (n = 19)
Mean HR (beats/min)632 ± 18 (n = 13)630 ± 13 (n = 19)
  • Data are means ± SEM.

  • aP < 0.05.

  • bP < 0.01.