Table 3.

Functional data from mice subjected to a high-potassium diet for 48 hours

ParameterKOControl
Serum Na+ (mM)147.6 ± 1.4 (n = 8)a151.5 ± 0.7 (n = 11)
Serum K+ (mM)7.7 ± 0.8 (n = 9)a5.2 ± 0.2 (n = 11)
Serum HCO3 (mM)12.8 ± 1.1 (n = 7)b18.3 ± 0.5 (n = 10)
Serum osm (mosm/kgH2O)329.0 ± 4.7 (n = 8)325.0 ± 1.5 (n = 9)
Serum creatinine (mM)19.1 ± 2.3 (n = 7)a12.1 ± 1.5 (n = 10)
Serum Cl (mM)114.4 ± 1.4 (n = 7)114.8 ± 0.7 (n = 10)
FE(Na+) (%)0.27 ± 0.05 (n = 7)0.25 ± 0.02 (n = 10)
  • Data are means ± SEM.

  • aP < 0.05.

  • bP < 0.001.