Table 3.

Follow-up after diagnosis of APRT deficiency

ParameterValue
Follow-up duration (months; median [IQR])74 (14 to 112)
Allopurinol therapy (n [%])35 (87.5)
Allopurinol dosage (median [IQR])
    adults (n = 22; mg/d)300 (200 to 300)
    children (n = 11; mg/kg per d)10 (9 to 10)
Stone recurrence (n [%])6 (15.0)
    treated by allopurinol (n = 35)5 (14.3)
    untreated (n = 5)1 (20.0)
Urologic procedures (n [%])
    030 (75.0)
    1 to 28 (20.0)
    >32 (5.0)
Type of urologic procedures (n [%])
    extracorporeal shock waves7 (17.5)
    ureteroscopy3 (7.5)
    percutaneous nephrolithotomy1 (2.5)
    surgery2 (5.0)
    nephrectomy2 (5.0)
Reaching ESRD during follow-up (n [%])2 (5.0)
Renal transplantation during follow-up (n [%])2 (5.0)
Total ESRD before or during follow-up (n [%])8 (20.0)
  • Data regarding follow-up for the 40 patients described in Table 2 are provided here.