Table 5.

Pregnancy outcome in 44 women with aHUS and genetic defects (CFH = 23, CFI = 9, MCP = 4, C3 =3, CFB = 2, more than one mutation = 3) and in 10 patients with aHUS and no detectable genetic defect

Number of PregnanciesFetal LossPreeclampsiaP-aHUSUneventful Pregnancy
Patients with genetic abnormality (n = 44)1035 (4.8%)8 (7.7%)18 (17.4%)77 (74.7%)
Patients with no genetic abnormality (n = 10)150 (0%)0 (0%)3 (20%)12 (80%)