Table 1.

Baseline characteristics of kidney allograft recipients with SLE according development of recurrence, rejection, or neither of those events

CharacteristicAll Recipients (n = 6850; 100%)Others Group (n = 4913; 71.72%)Rejection Group (n = 1770; 25.84%)Recurrence Group (n = 167; 2.44%)P
Age (years; mean ± SD)37 ± 1138 ± 12a34 ± 1133 ± 11<0.00001
Female gender (n [%])5605 (81.8)4010 (81.6)1447 (81.8)148 (88.6)0.069460
Race/ethnicity (n [%])<0.00001
    white non-Hispanic2878 (42.0)2109 (42.9)713 (40.3)56 (33.5)
    black non-Hispanic2406 (35.1)1581 (32.2)744 (42.0)81 (48.5)
    Hispanic1132 (16.5)879 (17.9)232 (13.1)21 (12.6)
    Rest434 (6.4)344 (7.0)81 (4.6)9 (5.4)
Pretransplantation dialysis status (n [%])b<0.00001
    yes6069 (90.8)4267 (88.6)1646 (96.5)156 (93.4)
    no541 (8.1)479 (10.0)53 (3.1)9 (5.4)
    unknown75 (1.1)66 (1.4)7 (0.4)2 (1.2)
    recipients treated for hypertension (n [%])c3302 (73.3)2735 (73.6)494 (72.2)73 (70.9)0.520156
Donor type (n [%])<0.00001
    deceased4205 (61.4)2839 (57.8)1265 (71.5)101 (60.5)
    living2645 (38.6)2074 (42.2)505 (28.5)66 (39.5)
Deceased-donor transplant HLA-A locus mismatch level (n [%])d0.00018
    21747 (41.6)1201 (42.3)495 (39.2)51 (50.5)
    11618 (38.5)1036 (36.5)547 (43.3)35 (34.7)
    0834 (19.9)599 (21.1)220 (17.4)15 (14.9)
Deceased-donor transplant HLA-B locus mismatch level (n [%])d0.02018
    21895 (45.1)1280 (45.1)571 (45.3)44 (43.6)
    11498 (35.7)976 (34.4)483 (38.3)39 (38.6)
    0806 (19.2)581 (20.5)207 (16.4)18 (17.8)
Deceased-donor transplant HLA-DR locus mismatch level (n [%])e0.028968
    21102 (26.6)750 (26.7)330 (27.0)22 (22.2)
    11851 (44.8)1223 (43.5)583 (47.7)45 (45.5)
    01183 (28.6)841 (29.9)310 (25.3)32 (32.3)
Deceased-donor transplant HLA mismatch level (n [%])f<0.00001
    6397 (9.6)288 (10.2)100 (8.2)9 (9.1)
    5907 (21.9)621 (22.1)262 (21.4)24 (24.2)
    41018 (24.6)689 (24.5)306 (25.0)23 (23.2)
    3776 (18.8)482 (17.1)275 (22.5)19 (19.2)
    2402 (9.7)254 (9.0)138 (11.3)10 (10.1)
    1159 (3.8)96 (3.4)58 (4.7)5 (5.1)
    0475 (11.5)383 (13.6)83 (6.8)9 (9.1)
Living-donor transplant haplotype match level (n [%])g0.000127
    2.0413 (17.6)348 (19.0)58 (12.8)7 (11.9)
    1.571 (3.0)61 (3.3)9 (2.0)1 (1.7)
    1.01251 (53.3)931 (50.8)288 (63.6)32 (54.2)
    0.592 (3.9)81 (4.4)8 (1.8)3 (5.1)
    0.0519 (22.1)413 (22.5)90 (19.9)16 (27.1)
Blood ABO type (n [%])h0.274332
    identical6082 (88.8)4341 (88.4)1588 (89.8)153 (91.6)
    compatible716 (10.5)533 (10.9)171 (9.7)12 (7.2)
    incompatible49 (0.7)37 (0.8)10 (0.6)2 (1.2)
Most recent PRA (%; mean ± SD)i14 ± 2612 ± 25a17 ± 2916 ± 29<0.00001
Previous pregnancies (mean [range])j1 (0 to 6)1 (0 to 6)1 (0 to 6)1 (0 to 6)0.60485
DGF (n [%])1045 (15.3)606 (12.3)424 (23.9)15 (8.9)<0.00001
Follow-up time (years; mean ± SD)4.95 ± 3.944.56 ± 3.87a5.89 ± 3.966.34 ± 3.69<0.00001
  • aP < 0.05, others group versus rejection or recurrence groups adjusted for multiple comparisons.

  • bA total of 165 missing values.

  • cA total of 2626 missing values.

  • dA total of six missing values.

  • eA total of 69 missing values.

  • fA total of 71 missing values.

  • gA total of three missing values.

  • hA total of 258 missing values.

  • iA total of 1258 missing values.

  • jA total of 1948 missing values