Table 2.

Blood Pi and creatinine clearance in Klotho−/− mice and WT CKD mice

Klotho−/− ModelCKD Model in WT Mice
WTKl−/−ShamCKD
Serum Pi (mg/dl)5.9 ± 0.48.1 ± 0.5a6.3 ± 0.67.1 ± 0.7b
ClCr (μl/min/g body wt)15.41 ± 1.0310.32 ± 2.14b10.22 ± 2.746.15 ± 1.13a
  • The data are represented as the means ± SEM (n ≥ 4).

  • aP < 0.01 versus Sham by unpaired t test.

  • bP < 0.05 versus WT by unpaired t test.