Table 2.

Associations between patient characteristics and likelihood of endogenous EPO status

AOR (95% CI)P
Demographics
    age (per 10 years older)0.97 (0.89 to 1.05)0.49
    men (versus women)3.27 (2.59 to 4.14)<0.0001
    black (versus non-black)1.07 (0.71 to 1.60)0.76
    ESRD vintage (per year)1.08 (1.06 to 1.09)<0.0001
    current smoker (versus no)1.42 (1.12 to 1.80)0.004
Comorbidities (yes versus no)
    coronary artery disease0.97 (0.78 to 1.20)0.78
    cancer0.89 (0.66 to 1.20)0.45
    cardiovascular disease (other than CAD or CHF)1.36 (1.12 to 1.66)0.002
    cerebrovascular disease1.24 (0.96 to 1.61)0.10
    congestive heart failure0.90 (0.71 to 1.14)0.36
    diabetes mellitus0.83 (0.57 to 1.21)0.33
    gastrointestinal bleeding0.68 (0.42 to 1.10)0.11
    HIV/AIDS0.42 (0.06 to 2.91)0.38
    hypertension0.58 (0.48 to 0.71)<0.0001
    lung disease1.39 (1.06 to 1.81)0.01
    neurologic disease0.75 (0.49 to 1.14)0.18
    psychiatric disorder0.95 (0.73 to 1.25)0.72
    peripheral vascular disease1.23 (0.97 to 1.55)0.09
    recurrent cellulitis/gangrene1.48 (1.04 to 2.10)0.03
Cause of ESRD (versus glomerulonephritis)
    diabetes mellitus1.01 (0.65 to 1.56)0.96
    hypertension0.68 (0.48 to 0.96)0.03
    cystic disease5.40 (4.02 to 7.25)<0.0001
    other0.82 (0.62 to 1.07)0.14
Laboratory/treatment measures
    BMI (per 1 kg/m2)1.07 (1.05 to 1.09)<0.0001
    albumin (per 0.5 g/dl)1.22 (1.09 to 1.37)0.0005
    PTH (per 100 pg/ml)1.02 (1.00 to 1.04)0.0571
    Tsat (per 1%)1.00 (0.99 to 1.01)0.91
    ferritin (per 100 ng/ml)0.87 (0.82 to 0.93)<0.0001
    catheter hemoaccess (versus other)0.53 (0.38 to 0.75)0.0003
    Kt/V (per 0.1)0.99 (0.96 to 1.03)0.67
    iron use (yes/no)0.42 (0.35 to 0.52)<0.0001
    active vitamin D use (yes/no)1.04 (0.87 to 1.25)0.64
  • AOR was adjusted for all factors listed plus DOPPS phase and region. CAD, coronary artery disease; CHF, congestive heart failure; Tsat, transferrin saturation.