Table 2.

Clock-controlled transport genes in the kidney

GeneFunctionRNA SourceReference
Slc9a3 (NHE3)Sodium/hydrogen exchangeWhole kidney66
GilzLeucine zipper protein/regulation of sodium transportDCT, CNT, CCD. Whole kidney61
Usp2Ubiquitin specific protease/regulation of sodium transportDCT, CNT, CCD. Whole kidney61
V1aRVasopressin receptor/regulation of water balanceDCT, CNT, CCD. Whole kidney61
V2RVasopressin receptor/regulation of water balanceDCT, CNT, CCD. Whole kidney61
Slc6a6Taurine transporterCCD61
Slc6a9Glycine transporterDCT/CNT61
Aqp2Water channelCCD61
Aqp4Water channelCCD61
Scnn1a (╬▒ENaC)Alpha subunit of epithelial sodium channelCortex, outer medulla and inner medulla65
  • DCT, distal convoluted tubule; CNT, connecting tubule; CCD, cortical collecting duct.