Table 2.

Pathologic markers of renal injury in TRPC6 WT and KO mice

Kidney DamageWT Mice (n = 11)KO Mice (n = 10)P
Mice with glomerular damage (sclerosis/collapse)72%40%0.13
Mice with podocyte damage (desmin +) (with or without glomerular damage)82%50%0.12
Mice with tubular microcysts (with or without glomerular or podocyte damage)92%60%0.10