Table 1.

Renal phenotype in β-catGOF-UB mice

Mutants/WTAplasiaDysplasia
Perinatal
    β-catGOF-UB11/36 (30.5%)5/11 (45%)6/11 (54.5%)
Embryonic
    β-catGOF-UB76/167 (40.2%)13/76 (17.1%)63/76 (82.8%)
  • Kidneys were isolated from newborn mice (P0) and from pregnant females at various gestational ages. In embryos in which kidney tissue could be identified, histology was analyzed and categorized as normal or dysplastic.