Table 1.

Baseline patient characteristics at dialysis initiation in Canada, 2001 to 2008

PD (n = 7,412)HD-AVF/AVG (n = 6,663)HD-CVC (n = 24,437)P
Era of dialysis initiation (%)<0.0001
    2001 to 200419.718.162.3
    2005 to 200818.916.664.6
Age (%)
    18 to 44 years15.49.511.0
    45 to 54 years16.712.511.1
    55 to 64 years22.620.219.4
    65 to 74 years25.229.126.9
    75+ years20.028.631.5
Race (%)<0.0001
    Caucasian70.476.575.8
    Asian8.65.85.0
    black3.42.83.4
    other12.610.011.2
    unknown5.04.94.6
Female gender (%)42.734.441.7
Primary renal diagnosis (%)<0.0001
    glomerulonephritis16.712.310.1
    diabetes36.238.435.4
    renal vascular disease17.220.220.1
    polycystic kidney disease6.97.72.2
    other11.811.218.5
    unknown11.210.213.7
Comorbidities (%)
    diabetes mellitus42.647.346.5<0.0001
    coronary artery diseasea24.832.036.1<0.0001
    peripheral vascular disease13.517.820.8<0.0001
    malignancy7.410.612.6<0.0001
    lung disease6.612.314.1<0.0001
    pulmonary edema12.918.628.6<0.0001
    hypertension85.486.680.1<0.0001
    current smoker12.112.013.8<0.0001
BMI (median, IQR) (kg/m2)26.0 (22.9, 29.6)27.1 (23.6, 31.6)25.9 (22.6, 30.3)<0.0001
Late referral (%)15.23.649.7<0.0001
Time from referral to dialysis initiation (median, IQR) (days)637 (212, 1490)851 (399, 1620)188 (11, 784)<0.0001
Hemoglobin (g/L)111 (101, 120)108 (98, 119)98 (87, 110)<0.0001
eGFR (ml/min per 1.73 m2)9.1 (7.1, 11.9)8.9 (7.0, 11.4)8.6 (6.3, 11.8)<0.0001
Serum albumin (g/L)36 (32, 40)35 (32, 39)31 (26, 36)<0.0001
  • IQR, interquartile range; eGFR, eGFR as determined by the modification of diet in renal disease formula.33

  • aCoronary artery disease was determined from the presence of a history of at least one of the following: coronary artery bypass grafting, previous myocardial infarction, or previous angina.