Table 3.

Associations between three measures of renal function and four outcomes: Bivariable linear and logistic regression results

Odds Ratio (95% CI; per 10 ml/min/1.73m2 decrease)P-valueC-statisticChange in Level (95% CI; per 10 ml/min/1.73m2 decrease)P-valueR2
AnemiaHemoglobin level (g/dl)
iGFR1.53 (1.43, 1.65)<0.00010.72iGFR−0.31 (−0.27, −0.36)<0.00010.13
eGFR_Cr1.57 (1.43, 1.72)<0.00010.67eGFR_Cr−0.38 (−0.31, −0.44)<0.00010.09
eGFR_cysC1.43 (1.34, 1.52)<0.00010.70eGFR_cysC−0.26 (−0.22, −0.30)<0.00010.11
iGFR1.59 (1.41, 1.79)<0.00010.72iGFR−0.30 (−0.22, −0.38)<0.00010.13
eGFR_Cr0.94 (0.81, 1.10)0.45eGFR_Cr−0.03 (0.09, −0.14)0.65
iGFR1.35 (1.20, 1.53)<0.00010.72iGFR−0.24 (−0.16, −0.33)<0.00010.14
eGFR_cysC1.14 (1.03, 1.27)0.01eGFR_cysC−0.08 (−0.00, −0.15)0.0497
HyperkalemiaPotassium level (mmol/L)
iGFR1.67 (1.35, 2.07)<0.00010.73iGFR0.08 (0.06, 0.09)<0.00010.08
eGFR_Cr1.86 (1.43, 2.42)<0.00010.72eGFR_Cr0.10 (0.08, 0.13)<0.00010.08
eGFR_cysC1.58 (1.29, 1.94)<0.00010.72eGFR_cysC0.06 (0.05, 0.08)<0.00010.07
iGFR1.45 (1.03, 2.06)0.040.73iGFR0.05 (0.02, 0.07)0.00020.09
eGFR_Cr1.25 (0.81, 1.93)0.32eGFR_Cr0.05 (0.02, 0.09)0.005
iGFR1.39 (0.97, 2.00)0.070.73iGFR0.05 (0.02, 0.08)0.00020.08
eGFR_cysC1.22 (0.88, 1.71)0.24eGFR_cysC0.02 (0.00, 0.05)0.04
Metabolic AcidosisBicarbonate level (mmol/L)
iGFR1.65 (1.49, 1.83)<0.00010.73iGFR−0.43 (−0.35, −0.51)<0.00010.08
eGFR_Cr1.92 (1.68, 2.19)<0.00010.73eGFR_Cr−0.65 (−0.53, −0.76)<0.00010.09
eGFR_cysC1.62 (1.46, 1.79)<0.00010.73eGFR_cysC−0.37 (−0.29, −0.44)<0.00010.08
iGFR1.36 (1.15, 1.60)0.00030.74iGFR−0.18 (−0.04, −0.32)0.010.09
eGFR_Cr1.38 (1.11, 1.71)0.004eGFR_Cr−0.44 (−0.24, −0.64)<0.0001
iGFR1.27 (1.07, 1.51)0.0060.74iGFR−0.27 (−0.12, −0.43)0.00040.09
eGFR_cysC1.34 (1.14, 1.58)0.0004eGFR_cysC−0.16 (−0.02, −0.29)0.02
HyperphosphatemiaPhosphate level (mg/dl)
iGFR1.45 (1.17, 1.79)0.00070.69iGFR0.09 (0.07, 0.10)<0.00010.07
eGFR_Cr1.81 (1.36, 2.42)<0.00010.71eGFR_Cr0.13 (0.11, 0.16)<0.00010.08
eGFR_cysC1.53 (1.23, 1.90)0.00010.72eGFR_cysC0.08 (0.07, 0.10)<0.00010.08
iGFR1.02 (0.71, 1.46)0.920.71iGFR0.03 (0.00, 0.06)0.040.08
eGFR_Cr1.77 (1.08, 2.93)0.02eGFR_Cr0.09 (0.05, 0.14)<0.0001
iGFR0.99 (0.69, 1.42)0.960.72iGFR0.03 (−0.01, 0.06)0.100.08
eGFR_cysC1.54 (1.07, 2.21)0.02eGFR_cysC0.06 (0.03, 0.09)<0.0001