Table 1.

Results of single SNP association analysis

ChrSNPPosition (kb)Minor AlleleMAF ControlsIgAN (35 Cases and 74 Controls)FSGS (44 Cases and 74 Controls)HIVAN (21 Cases and 74 Controls)FSGS + HIVAN (65 Cases and 74 Controls)
MAF CasesORaPbMAF CasesORaPbMAF CasesORaPbMAF CasesORaPb
22rs7388531936,661G0.2640.2140.760.43 (NS)0.5002.802.3 × 10−40.4552.331.6 × 10−20.4922.718.1 × 10−5
22rs6091014536,662G0.2500.2140.820.56 (NS)0.4892.871.8 × 10−40.4552.509.1 × 10−30.4852.824.8 × 10−5
22rs7178531336,662Del0.1350.2001.600.22 (NS)0.2502.132.6 × 10−20.2502.136.9 × 10−20.2462.091.8 × 10−2
22rs1191276336,684A0.1820.2291.330.42 (NS)0.3862.825.4 × 10−40.4323.416.7 × 10−40.4002.996.0 × 10−5
22rs482148136,696T0.3240.3531.140.68 (NS)0.2270.611.1 × 10–10.1590.393.3 × 10−20.2080.552.9 × 10−2
22rs575025036,708A0.4390.4411.010.98 (NS)0.2560.445.1 × 10−30.1820.282.0 × 10−30.2310.382.6 × 10−4
  • IgAN, IgA nephropathy; FSGS, focal segmental glomerulosclerosis; HIVAN, HIV-1-associated nephropathy; Chr, chromosome; SNP, single-nucleotide polymorphism; MAF, minor allele frequency; NS, not significant.

  • aOR corresponds to the odds ratio per one copy of the minor allele.

  • bP value corresponds to the allelic test of association.