Table 3.

Comparison of microalbuminuria and stage 3 to 5 CKD rates between African Americans with no or one risk allele, two APOL1 risk alleles, and European Americans

European American No Risk AllelesAfrican AmericanP
No or One Risk AllelesTwo Risk AllelesAA (no or one) versus EAAA (two) versus EA
Microalbuminuria (%)
    total3.459.1717.540.000331.72 × 10−8
    nondiabetic (n = 1559)2.315.9516.500.000731.3 × 10−9
    diabetic (n = 266)17.5727.3525.000.1670.592
GFR4 < 60 ml/min per 1.73 m2 (%)
    total2.042.475.510.260.042
    nondiabetic (n = 1559)1.571.685.770.480.0039
    diabetic (n = 266)8.116.993.570.280.30
GFR6 < 60 ml/min per 1.73 m2 (%)
    total1.952.606.360.360.0080
    nondiabetic (n = 1559)1.471.686.730.530.00039
    diabetic (n = 266)8.117.863.570.390.30