Table 3.

Relationship between nonspecific lesions of arteries/arterioles and TMA in normotensive and hypertensive patients (MHT excluded)

Normotensive PatientsHypertensive Patients
TMA PresentTMA AbsentP ValueTMA PresentTMA AbsentP Value
Number of patients20433013
Lesion
 arteriosclerosis (global)2.21 (2–3)1.14 (0–2)0.00042.57 (2–3)1.69 (1–2)0.003
 arterial intimal sclerosis1.20 (0–2)0.54 (0–1)0.011.85 (1–2.5)0.71 (0–1)0.001
 arterial S/M hypertrophy0.60 (0–1)0.39 (0–1)>0.100.85 (0–2)0.20 (0.–0.25)0.02
 arterial S/M hyalin deposits0.30 (0–1)0.15 (0–0)>0.100.58 (0–1)0.08 (0–0)0.01
 arteriolar lumen caliber2.25 (2–3)2.77 (3–3)0.00022.25 (2–3)2.76 (3–3)0.01
 arteriolar S/M hypertrophy0.1 (0–0)0.01 (0–0)>0.100.62 (0–1)0.23 (0–0)0.02
 arteriolar hyalin deposits1.20 (0.5–2)0.51 (0–1)0.010.93 (0–2)1.31 (0–2)>0.10
  • MHT cases could not be broken down in this fashion because all patients had some form of TMA. Values expressed as mean (25th to 75th percentile). P values calculated by Mann–Whitney U test. S/M, smooth muscle.