Table 1.

Renal tubular ion transporters affected by thyroid hormone

Na+-K+ ATPase
Na+-HCO3 exchanger
Na+-H+ exchanger
Na+-Pi IIa exchanger
Na+-sulfate exchanger
Na+-K+-2Cl cotransporter
Na+-Ca2+ exchanger
Cl channel
AQP 1 and 2
  • Transporter function is decreased with hypothyroidism and increased with hyperthyroidism or thyroid hormone replacement with the exception of AQP, which has the opposite pattern.5460 AQP, aquaporin.