Table 2.

Changes in biochemical measures

VariableBaseline (n=15)3-Month Follow-up (n=15)6-Month Follow-up (n=8)P Value
Plasma creatinine (µmol/L)186.7±64.4184.7±57.3217.4±600.28
Urea (mmol/L)23.9±10.923.4±10.821.9±12.60.73
Creatinine eGFR (mL/min per 1.73 m2)31.2±8.932.6±8.929.04±7.30.22
Cystatin C eGFR (mL/min per 1.73 m2)24.5±10 (n=7)26.2±13.5 (n=7)31.5±15.3 (n=4)0.68
Cystatin C (mg/L)2.14±0.452.11±0.541.99±0.670.74
Sodium (mmol/L)140.4±4.4140.2±2.9141.0±3.20.97
Potassium (mmol/L)4.4±0.54.6±0.74.2±0.60.12
Hemoglobin (g/L)119.7±15.7126.2±16124.9±12.40.08
Hemoglobin A1c (%)8.31±2.48.12±2.037.64±1.620.82
BNP (ng/L)564±391469±428372±3860.17
UACR (mg/g)592±955533±956355±2760.21
Total cholesterol (mmol/L)4.96±1.794.84±1.734.23±0.790.97
LDL cholesterol (mmol/L)2.7±0.72.7±0.92.38±0.60.82
HDL cholesterol (mmol/L)1.06±0.41.04±0.31.01±0.20.94
Triglycerides (mmol/L)2.41±2.32.42±2.21.97±0.80.76
24-hr creatinine clearance in urine (mL/min per 1.73 m2)43.9±12.446.5±15.345.0±8.20.64
Proteinuria (g/24 hr)1.41±0.520.82±0.360.81±0.760.24
Sodium excretion in urine (mmol/24 hr)169.3±56.7187.3±59.4152.0±86.90.77
Potassium excretion urine (mmol/24 hr)90.3±23.888.3±22.867.0±34.10.22
  • Data are mean ± SD. eGFR, estimated GFR; UACR, urinary albumin-to-creatinine ratio.