Table 2.

Mean bias and accuracies according to age groups and equations

GroupCGMDRDCKD-EPISchwartz 2009Schwartz-Lyon
All measurements (n=1054)
 mGFR=88.7±30.8
 eGFR123.0±45.3122.9±56.6116.7±34.085.8±27.781.8±27.7
 correlation coefficient (r)0.830.760.800.850.86
 mean ratio (eGFR/mGFR)1.42±0.351.41±0.471.38±0.361.00±0.220.95±0.20
 95% limits of agreement0.73, 2.100.48, 2.320.69, 2.060.55, 1.450.55, 1.34
 10% accuracy15221838a36a
 30% accuracy41504986a87a
Group 1 (10–12 yr) (n=225)
 mGFR=93.4±29.3
 eGFR150.9±45.2179.3±59.0144.6±25.698.6±25.688.7±25.0
 correlation coefficient (r)0.870.840.840.880.89
 mean ratio (eGFR/mGFR)1.65±0.321.95±0.421.65±0.391.10±0.210.98±0.18
 95% limits of agreement1.02, 2.281.13, 2.770.89, 2.410.69, 1.510.63, 1.33
 10% accuracy11347a48a
 30% accuracy104178692b
Group 2 (13–17 yr) (n=322)
 mGFR=87.3±32.5
 eGFR127.1±45.4125.3±50.9119.9±32.587.2±28.385.7±29.7
 correlation coefficient (r)0.880.860.850.890.89
 mean ratio (eGFR/mGFR)1.50±0.331.46±0.371.44±0.321.04±0.211.01±0.20
 95% limits of agreement0.85, 2.150.74, 2.180.81, 2.070.63, 1.450.62, 1.40
 10% accuracy6141041a37a
 30% accuracy3141388890
Group 3 (18–21 yr) (n=262)
 mGFR=90.4±30.1
 eGFR113.2±39.3102.9±40.1106.9±30.582.0±26.479.4±27.3
 correlation coefficient (r)0.850.850.860.860.85
 mean ratio (eGFR/mGFR)1.28±0.291.16±0.301.23±0.270.94±0.220.90±0.41
 95% limits of agreement0.71, 1.850.57, 1.750.96, 1.560.51, 1.370.49, 1.31
 10% accuracy2536273228
 30% accuracy59756984a83a
Group 4 (22–25 yr) (n=245)
 mGFR=84.1±30.3
 eGFR102.5±35.589.3±31.897.3±28.476.0±25.773.0±25.2
 correlation coefficient (r)0.850.850.860.860.85
 mean ratio (eGFR/mGFR)1.27±0.311.10±0.271.21±0.280.94±0.210.90±0.23
 95% limits of agreement0.66, 1.870.57, 1.630.66, 1.760.53, 1.350.45, 1.35
 10% accuracy2936333331
 30% accuracy6478728582
  • mGFR and eGFR are measured in milliliters per minute per 1.73 m2.

  • a P<0.05 between pediatric formulas and other equations, favoring pediatric equations, but without significant difference between Schwartz 2009 and Schwartz-Lyon.

  • b P<0.05 between pediatric formulas and other equations, favoring Schwartz-Lyon. All results are expressed as mean ± SD.