Table 2.

Patients with at least one serious adverse event in the study group as a whole (overall) and according to disease outcome (complete, partial, or no remission)

Serious Adverse EventOverallComplete RemissionPartial RemissionNo Remission
Fatal4013
 cardiovascular3012
  stroke1010
  acute MI2002
 cancera1001
Nonfatal7124
 cardiovascular5113
  stroke2002
  acute MIb1010
  TIA2101
 cancerc2011
Total11137
  • The incidence of events in participants with complete remission was lower than in those with partial or no remission (P=0.037, Cochran–Armitage test for trend). MI, myocardial infarction; TIA, transitory ischemic attack.

  • a Lung cancer.

  • b Event during a relapse of nephrotic syndrome.

  • c Breast and prostate cancer.