Table 3.

Office and ambulatory BP and heart rate before and after renal denervation

MeasurementBaseline (n=15)3-Month Follow-up (n=15)6-Month Follow-up (n=8)P Values
Baseline versus 3-Month Follow-upBetween Treatments
SBP
 office (mmHg)174±22147±29145±18<0.001<0.001
 ABPM mean (mmHg)159±14153±16154±210.240.49
 ABPM daytime (mmHg)160±14156±19160±140.530.84
 ABPM night-time (mmHg)154±16140±22144±220.030.10
 maximum night-time (mmHg)185±19171±22166±330.040.14
 dipping status (%)4±611±910±90.010.04
 rate of rise (mmHg/hr)12.07±7.72.09±1.64.8±6.10.050.03
 BP power surge (log) (mmHg)1.6±1.80.6±1.01.4±1.00.010.03
 Night-to-day ratio0.96±0.060.89±0.080.89±0.080.010.04
DBP
 office (mmHg)91±1677±1977±190.0020.001
 ABPM mean (mmHg)85±1278±679±110.080.11
 ABPM daytime (mmHg)83±1380±1083±130.210.38
 ABPM night-time (mmHg)78±1170±875±140.020.02
 Maximum night-time (mmHg) 93±1584±1494±190.170.44
 Dipping status (%)6±712±1010±70.010.02
 Night-to-day ratio0.94±0.070.88±0.090.90±0.070.010.02
Heart rate
 office (beats/min)64±966±1264±130.540.72
 ABPM mean (beats/min)64±1167±1064±120.120.28
 ABPM daytime (beats/min)65±964±965±130.550.8
 ABPM night-time (beats/min)65±963±863±120.330.57
 Night-to-day ratio0.98±0.060.96±0.060.98±0.060.360.38
  • Values are expressed as mean ± SD. Data are shown as a one-way repeated-measures ANOVA between treatments. 24-hr daytime, night-time, and maximum night-time BP; rate of SBP increase; BP power surge; and night-to-day ratios were obtained in limited number of patients at baseline (n=10), at 3 months (n=10), and at 6 months (n=6). ABPM, ambulatory BP monitoring.