Table 2.

Related adverse events on study

Related Adverse EventAll Active (n=88)All Placebo (n=57)Lanthanum (n=28)Sevelamer (n=30)Calcium (n=30)
One or more adverse events (n; %)31128 (29)10 (33)13 (43)
Constipation (n; %)1102 (7)5 (17)4 (13)
Diarrhea (n; %)515 (18)
Dyspepsia (n; %)411 (4)1 (3)2 (7)
Hypercalcemia (n; %)505 (17)
Vomiting (n; %)414 (14)
Flatulence (n; %)221 (4)1 (3)
Nausea (n; %)313 (11)
Hypophosphatemia (n; %)211 (4)1 (3)
Abdominal pain (n; %)02
Acidosis (n; %)201 (4)1 (3)
Myalgia (n; %)111 (3)
AKI (n; %)101 (3)
Dysgeusia (n; %)01
GERD (n; %)101 (3)
Hyperparathyroidism (n; %)01
Hypothyroidism (n; %)01
  • Fisher exact test for all active versus all placebo. GERD, gastro-esophageal reflux disease.