Table 1.

Characteristics of the selected IgAN patients (n=97) at time of diagnosis and last follow-up and according to the ARR of dialysis or death

CharacteristicIgAN
ARR = 0IgAN
ARR = 1IgAN
ARR = 2IgAN
ARR = 3StatisticsIgAN
All Patients
Patients (n)2522252597
Men 16 (64)16 (73)18 (72)23 (92)NS73 (75)
At diagnosis
 age (yr)37.8 (12.1)40.2 (12.4)45.7 (12.9)50.0 (16.1)43.6 (14.2)
 proteinuria (g/d)0.16 (0.22)0.90 (0.93)1.58 (1.04)3.56 (2.27)1.59 (1.87)
  class 0: <0.3019 (76)6 (27)2 (8)0 (0)27 (28)
  class 1: 0.30–0.996 (24)8 (36)6 (24)0 (0)χ2=79.0320 (21)
  class 2: 1.00–2.990 (0)7 (32)14 (56)11 (44)P<0.000132 (33)
  class 3: ≥3.000 (0)1 (4)3 (12)14 (56)18 (19)
  proteinuria ≥1 g/d 0 (0)8 (36)16 (64)25 (100)χ2=53.5949 (50)
P<0.0001
 hypertension0 (0)10 (46)15 (60)25 (100)χ2=51.5450 (52)
P<0.0001
 GOS5.1 (1.2)6.0 (2.0)8.7 (1.9)13.3 (2.9)8.3 (3.8)
  GOS ≥8 U0 (0)4 (18)19 (76)25 (100)χ2=65.6748 (50)
P<0.0001
 eGFR (ml/min per 1.73 m2)82.0 (14.9)80.4 (22.3)64.2 (29.4)28.3 (25.7)63.2 (32.0)
  stage 17 (28)6 (27)6 (24)1 (4)20 (21)
  stage 2 17 (68)12 (54)9 (36)2 (8)χ2=61.3040 (41)
  stage 31 (4)4 (18)5 (20)6 (24)P<0.000116 (16)
  stage 40 (0)0 (0)5 (20)5 (20)10 (10)
  stage 5 0 (0)0 (0)0 (0)11 (44)11 (11)
At last follow-up:
 exposure time (yr)13.8 (8.2)10.3 (6.1)15.4 (11.2)15.1 (12.1)13.8 (9.8)
 eGFR (ml/min per 1.73 m2)81.3 (17.7)72.9 (29.3)59.9 (35.6)16.9 (18.4)57.3 (36.1)
  stage 1 7 (28)8 (36)6 (24)0 (0)21 (22)
  stage 2 16 (64)9 (41)8 (32)1 (4)34 (35)
  stage 3 2 (8)3 (14)6 (24)4 (16)χ2=58.3315 (16)
  stage 4 0 (0)0 (0)1 (4)3 (12)P<0.00014 (4)
  stage 5 0 (0)2 (9)4 (16)17 (68)23 (24)
 dialysis 0 (0)2 (9)3 (12)16 (64)χ2=36.7621 (22)
P<0.0001
 death2 (8)0 (0)2 (8)1 (4)NS5 (5.2)
 D/D event 2 (8)2 (9)5 (20)17 (68)χ2=30.2426 (27)
P<0.0001
  • Data are n (%) or mean (SD). D/D, outcome of dialysis/death; NS, not statistically significant.