Table 4.

Metabolic profile in CKD mice fed or not fed with an AXOS prebiotic–enriched diet

DietStandard MiceAXOS MiceChange (%)P Value
Fasting insulin (pg/ml)60.5±1138±17−370.12
Fasting glucose (mg/dl)97±581±2−160.002
HOMA-IR1.8±0.41.0±0.2−440.09
Triacylglycerols (mg/dl)118±1276±10−360.02
Total cholesterol (mg/dl)123±1180±10−350.01
Adiponectin (μg/ml)25±326±140.47
Urea (mmol/L)34±330±3−130.29
MDA (μM)10.3±3.911.1±2.780.73
  • Data are mean ± SEM and variation compared with control group. Differences were considered significant at the P<0.05 level using ANOVA test. n=5–6 mice for each group. HOMA-IR, homeostasis model assessment insulin resistance; MDA, malondialdehyde.