Table 3.

Multivariate mixed logistic regression analysis of factors predicting subtarget Hb levels.

VariableModel 1 (Excluding Serum Ferritin; n=3073)Model 2 (Including Serum Ferritin; n=1781)
Odds Ratio (95% CI)P ValueOdds Ratio (95% CI)P Value
Age at study entry (yr)1.03 (1.01–1.05)0.011.02 (0.996–1.05)0.10
Time on PD before study entry (yr)1.04 (0.98–1.11)0.211.05 (0.96–1.14)0.27
Study time (yr)0.96 (0.86–1.08)0.540.93 (0.81–1.07)0.33
Pubertal male0.51 (0.38–0.70)<0.0010.50 (0.32–0.74)<0.001
Residual urine output (L/m2 per day)0.73 (0.62–0.85)<0.0010.81 (0.66–0.99)0.04
PD fluid turnover (L/m2 per day)0.96 (0.93–0.99)0.010.94 (0.90–0.98)0.01
Use of biocompatible PD fluids0.73 (0.59–0.91)0.0050.70 (0.52–0.93)0.01
Use of long-acting ESA0.995 (0.78–1.28)0.970.97 (0.71–1.32)0.84
Use of intravenous iron0.87 (0.67–1.13)0.300.85 (0.62–1.17)0.31
ACE/ARB treatment1.05 (0.85–1.29)0.661.17 (0.89–1.53)0.27
Serum PTH (log; pg/ml)1.33 (1.22–1.44)<0.0011.35 (1.22–1.50)<0.001
Serum albumin (g/L)0.94 (0.92–0.95)<0.0010.93 (0.91– 0.95)<0.001
Serum ferritin (log; ng/ml)1.43 (1.26–1.61)<0.001
Time since last peritonitisa (mo)1.00 (0.99–1.01)0.9981.00 (0.99–1.01)0.64
  • For variables with units given in parentheses, odds ratios refer to change in likelihood per unit change (e.g., an odds ratio of 0.73 indicates a 27% risk decrease per 1 L/m2 per day urine output). CI, confidence interval; ACE, angiotensin-converting enzyme; ARB, angiotensin-receptor blocker.

  • a For observations in patients without previous peritonitis episodes, the study entry date minus 1 year was arbitrarily entered.