Table 2.

Definitions of steroid-resistant, steroid dependent, and frequently relapsing MCD

Steroid resistantaFailed to achieve remission with 16 wk of daily or alternate-day steroids
Steroid dependentaTwo or more relapses during steroid taper or within 2 wk of discontinuing steroid therapy
Frequently relapsingbTwo or more relapses within 6 mo or four or more relapses within 1 yr of achieving remission
  • a Adapted from adult FSGS guidelines in reference 37.

  • b No formal definition exists in adults; adapted from the definition for children with FR MCD from reference 37.