Table 1.

Example of an increasing plasma creatinine in step decrement AKI

DayHours between Creatinine MeasurementsPlasma Creatinine (mg/dl)Kinetic eGFR Formula (ml/min)
0.001.1091
23
0.962.2910.17
12
1.462.859.87
14
2.043.459.99
20
2.884.2210.02
26
3.965.099.99
27
5.085.869.94
22
6.006.3910.04
  • The plasma creatinine rises precipitously in severe AKI, usually by >0.5 mg/dl per day. The differing numbers of hours between creatinine measurements are listed, resulting in fractional days, but 6 days of data are shown. Between successive pairs of creatinines, the eGFR by the kinetic formula has been calculated in the last column. The rate of creatinine rise starts to slow down eventually, but the abrupt drop in kidney function persists, reminiscent of the shape of a step, hence step decrement.