Table 3.

Adjusted HRs of myocardial infarction for eGFR subgroups

LDL-C Category (mmol/L)HR (95% CI)
eGFR=15–59.9 ml/min per 1.73 m2 (n=47,092)eGFR=60–89.9 ml/min per 1.73 m2 (n=351,849)eGFR≥90 ml/min per 1.73 m2 (n=437,119)
<2.60.93 (0.82, 1.04)0.93 (0.85, 1.01)0.98 (0.87, 1.12)
2.6–3.391.001.001.00
3.4–4.091.22 (1.06, 1.39)1.20 (1.11, 1.30)1.35 (1.19, 1.52)
4.1–4.891.68 (1.42, 1.99)1.39 (1.26, 1.54)1.99 (1.73, 2.29)
≥4.92.06 (1.59, 2.67)2.30 (2.00, 2.65)3.01 (2.46, 3.69)
  • Referent category is LDL-C=2.6–3.39. Adjusted for age, sex, diabetes, hypertension, Aboriginal status, socioeconomic status, proteinuria categories, statin use, and Charlson comorbidities (cancer, cerebrovascular disease, congestive heart failure, chronic pulmonary disease, dementia, metastatic solid tumor, myocardial infarction, liver disease, hemiplegia/paraplegia, peptic ulcer disease, peripheral vascular disease, and rheumatic disease).