Table 2.

Incidence rates and adjusted HRs for ESRD associated with each Life’s Simple 7 factor

Life Simple 7 FactorLife Simple 7 Factor Level
PoorIntermediateIdeal
ESRD incidence rates (95% CI)a
 Cigarette smoking19.7 (13.1 to 29.6)b12.4 (10.5 to 14.7)
 Physical activity16.4 (13.3 to 20.2)11.8 (8.8 to 15.8)8.7 (5.9 to 12.7)
 Body mass index17.0 (13.7 to 21.1)10.7 (8.1 to 14.1)10.4 (7.3 to 14.9)
 Diet11.3 (9.0 to 14.1)8.8 (5.1 to 15.1)
 BP23.3 (18.8 to 28.9)9.5 (7.6 to 11.9)4.3 (1.6 to 11.4)
 Cholesterol18.2 (12.1 to 27.4)11.4 (9.2 to 14.2)14.5 (11.1 to 18.9)
 Glucose22.0 (16.1 to 30.1)20.1 (16.2 to 25.0)6.1 (4.5 to8.3)
HR (95% CI)c
 Cigarette smoking1 (reference)0.79 (0.50 to 1.23)
 Physical activity1 (reference)0.66 (0.46 to 0.94)0.50 (0.32 to 0.78)
 Body mass index1 (reference)0.80 (0.55 to 1.14)0.94 (0.61 to 1.44)
 Diet1 (reference)1.01 (0.50 to 2.04)
 BP1 (reference)0.43 (0.32 to 0.60)0.26 (0.09 to 0.70)
 Cholesterol1 (reference)0.66 (0.41 to 1.05)0.83 (0.50 to 1.36)
 Glucose1 (reference)1.07 (0.73 to 1.56)0.38 (0.24 to 0.59)
  • Supplemental Appendix has definitions of poor, intermediate, and ideal levels.

  • a Incidence rates per 1,000 person-years.

  • b Too few individuals in these groups to produce incidence rates or HRs.

  • c HRs are adjusted for age, race, sex, geographic region of residence, income, education, and history of stroke and coronary heart disease.