Table 1.

Baseline characteristics of REGARDS study participants with an eGFR<60 ml/min per 1.73 m2 by number of ideal Life’s Simple 7 factors

CharacteristicOverall Population (n=3093)Number of Ideal Life’s Simple 7 Factors
0–1 (n=845)2 (n=1062)3 (n=767)4 (n=337)5–7 (n=82)
Age, yr72.2 (8.7)69.8 (8.2)72.2 (8.6)73.6 (8.8)74.7 (8.6)75.3 (9.3)
African American, %42.354.441.137.930.023.2
Men, %45.138.544.848.253.751.2
Geographic region, %
 Stroke belt32.634.133.430.134.123.2
 Stroke buckle20.823.018.622.419.617.1
 Other46.643.047.947.546.359.8
Household income<$20,000/yr, %24.336.326.923.724.714.3
Less than high school education, %19.223.118.616.818.114.6
Physically active, %54.036.851.064.274.590.2
Current smoker, %10.521.48.95.13.60.0
Diet factors
 Fish consumption, g/wk22.0 (29.0)24.0 (34.6)21.8 (25.7)21.0 (28.0)19.5 (22.8)26.8 (37.7)
 Sodium intake, mg/d2140 (1015)2121 (1074)2202 (1053)2060 (939)2175 (981)2170 (758)
 Sugar, mg/d249 (203.4)226 (197)257 (207)249 (199)273 (219)261 (177)
 Fruits and vegetables, cups/wk4.1 (2.3)3.9 (2.3)4.1 (2.3)4.0 (2.3)4.2 (2.3)5.2 (2.4)
 Fiber/carbohydrate intake ratio0.08 (0.03)0.08 (0.03)0.08 (0.03)0.08 (0.03)0.08 (0.03)0.09 (0.03)
Body mass index, kg/m229.6 (6.4)32.5 (6.0)30.4 (6.1)27.8 (5.9)25.0 (4.5)23.6 (4.3)
Fasting serum glucose, mg/dl105 (37)123 (50)103 (33)96 (22)91 (13)87 (8)
Antiglycemic medication use, %31.265.931.714.63.71.3
Diabetes mellitus, %35.170.133.715.74.31.3
Total cholesterol, mg/dl186 (43)190 (48)189 (43)184 (42)180 (33)169 (31)
Lipid-lowering medication use, %46.372.449.033.816.26.1
Systolic BP, mmHg130.8 (18)133 (18)132 (18)130 (18)128 (17)115 (14)
Diastolic BP, mmHg75 (11)75 (11)75 (10)75 (11)73 (10)69 (10)
Antihypertensive medication use, %76.190.882.771.058.732.1
Hypertension, %80.890.485.276.365.031.7
Renin angiotensin system blockers, %58.069.761.549.243.335.4
Coronary heart disease, %31.738.332.027.825.223.2
Stroke, %13.014.713.112.510.19.8
eGFR, ml/min per 1.73 m247.1 (10.9)45.1 (12.0)46.9 (10.5)48.4 (10.4)48.5 (9.8)50.6 (8.2)
Geometric mean (95% CI) ACR, mg/g23.8 (22.3 to 25.4)39.4 (34.2 to 45.4)23.5 (21.0 to 26.3)18.5 (16.4 to 20.8)14.4 (12.4 to 16.8)13.7 (10.3 to 18.2)
  • Supplemental Appendix has listing and definitions of ideal levels for each Life’s Simple 7 factor. ACR, albumin-to-creatinine ratio.