Table 3.

The association of first dialysis access placed with patient mortality from the time of ESRD for the comorbidities of malignancy, diabetes, and PVD in age-specific population subgroups by proportional hazards model

Risk GroupOutcome: Patient Mortality after ESRD (HD Initiation)
Access Type: GraftAccess Type: Catheter
Hazard Ratio (95% CI)PHazard Ratio (95% CI)P
67–79 yr (n=74,997)
 History of malignancy1.12 (0.91–1.38)0.271.87 (1.71–2.05)<0.001
 No history of malignancy1.09 (1.02–1.18)0.011.78 (1.72–1.83)<0.001
 History of diabetes1.10 (1.01–1.20)0.021.78 (1.71–1.85)<0.001
 No history of diabetes1.09 (0.97–1.23)0.141.81 (1.72–1.91)<0.001
 History of PVD1.12 (0.97–1.29)0.121.66 (1.56–1.77) <0.001
 No history of PVD1.09 (1.01–1.18)0.031.83 (1.77–1.89)<0.001
80–89 yr (n=37,149)
 History of malignancy1.31 (1.02–1.67)0.031.90 (1.70–2.13)<0.001
 No history of malignancy0.94 (0.85–1.03)0.191.68 (1.61–1.76)<0.001
 History of diabetes0.98 (0.85–1.12)0.741.68 (1.58–1.78)<0.001
 No history of diabetes0.98 (0.86–1.11)0.721.76 (1.67–1.85)<0.001
 History of PVD0.97 (0.79–1.20)0.771.59 (1.45–1.73)<0.001
 No history of PVD0.98 (0.88–1.09)0.691.76 (1.68–1.84)<0.001
≥90 yr (n=3279)
 History of malignancy1.40 (0.31–6.44)0.661.65 (1.07–2.55)0.02
 No history of malignancy1.03 (0.69–1.55)0.871.77 (1.49–2.10)<0.001
 History of diabetes1.09 (0.58–2.02)0.791.51 (1.10–2.07)0.01
 No history of diabetes1.04 (0.63–1.73)0.861.86 (1.55–2.24)<0.001
 History of PVD1.27 (0.30–5.42)0.741.63 (1.08–2.47)0.02
 No history of PVD1.10 (0.74–1.65)0.631.80 (1.51–2.13)<0.001
  • Fistula group was used as the reference. The Cox models were adjusted for age at ESRD onset, race, sex, BMI, comorbidity index, type of first access placed, duration of pre-ESRD nephrology care, and primary cause of ESRD. 95% CI, 95% confidence interval.