Table 2.

Correlations between biomarkers indexed to urinary creatinine and clinical traits

BiomarkerAgeBMISBPGlucoseHDL CholesterolTriglycerideseGFRCystatin CUACRa
α1-microglobulin0.14b−0.04c0.12b0.10b−0.05d0.06b−0.09b0.21b0.22b
β2-microglobulin0.06b−0.0020.05c0.04c−0.04c0.03−0.09b0.21b0.16b
Calbindin0.06b0.0070.08b0.01−0.008−0.005−0.008−0.010.12b
Clusterin0.03−0.05c0.002−0.06b0.07b−0.04c−0.001−0.04c0.10b
CTGF0.07b−0.05d0.02−0.030.06d−0.040.040.030.13b
Cystatin-C0.04c0.0040.04c0.01−0.020.03−0.09b0.16b0.13b
GST-α0.03−0.010.02−0.010.02−0.03−0.020.010.07b
Kim-10.19b0.020.13b0.08b0.0030.05d−0.030.17b0.19b
NGAL0.06b−0.020.020.010.04c0.03−0.06d0.040.15b
Osteopontin0.010.06d0.0060.02−0.05d0.0010.04c−0.03−0.17
TFF-30.02−0.08b0.020.0080.10b0.03−0.06d0.07b0.001
Tamm–Horsfall Protein0.02−0.12b−0.02−0.13b0.16b−0.08b0.04−0.09b0.02
TIMP-10.04c−0.0010.010.02−0.03−0.02−0.030.020.06b
VEGF0.07b−0.04c0.03−0.004−0.04c−0.02−0.05c0.05d0.10b
  • SBP, systolic BP; TIMP-1, tissue inhibitor of matrix metalloproteinase-1; VEGF, vascular endothelial growth factor.

  • a To avoid spurious correlation caused by creatinine being the denominator in both cases, the correlation with biomarker unindexed to urinary creatinine is presented for UACR.

  • b P<0.001.

  • c P<0.05.

  • d P<0.01.