Table 6.

Predictors of survival

VariableIncidentPrevalent
Hazard Ratio (95% CI)P ValueHazard Ratio (95% CI)P Value
Dialysate TNF-α0.99 (0.34 to 2.89)0.980.86 (0.22 to 3.43)0.8
Dialysate IL-60.93 (0.66 to 1.31)0.70.96 (0.65 to 1.44)0.9
Dialysate IFN-γ1.18 (0.69 to 2.00)0.51.20 (0.65 to 2.19)0.6
Plasma IL-1β0.56 (0.15 to 2.15)0.40.52 (0.16 to 1.74)0.3
Plasma TNF-α3.39a (1.26–9.16)0.022.03 (0.52 to 7.93)0.3
Plasma IL-62.15b (1.22 to 3.78)0.0082.68b (1.28 to 5.58)0.009
Plasma IFN-γ0.89 (0.49 to 1.60)0.71.16 (0.62 to 2.16)0.6
Age (per yr)1.06b (1.05 to 1.08)<0.0011.06b (1.04 to 1.07)<0.001
Male sex0.94 (0.69 to 1.29)0.71.28 (0.92 to 1.78)0.1
Comorbidity (per disease)1.68b (1.44 to 1.96)<0.0011.37b (1.18 to 1.58)<0.001
Urine volume (per L)0.95 (0.76 to 1.19)0.70.65b (0.48 to 0.87)0.004
Duration of PD (per mo)1.17 (0.05 to 29.16)0.91.14b (1.04 to 1.24)0.005
Albumin (per 1 g/dl)0.94b (0.91 to 0.97)<0.0010.99 (0.95 to 1.03)0.6
PSTR (per 0.1 increase in dialysate-to-plasma creatinine ratio)1.10 (0.98 to 1.23)0.11.18a (1.003 to 1.41)0.049
Body mass index1.01 (0.97 to 1.05)0.61.01 (0.98 to 1.04)0.6
  • Models stratified by center. Cytokine hazard ratios are for each 1×log10 change in concentration. CI, confidence interval.

  • a P=0.01–0.05.

  • b P<0.01.